{"id":2717,"date":"2023-12-26T23:43:44","date_gmt":"2023-12-26T14:43:44","guid":{"rendered":"https:\/\/u-lab.my-pharm.ac.jp\/~mminfo\/?p=2717"},"modified":"2023-12-26T23:43:44","modified_gmt":"2023-12-26T14:43:44","slug":"%e5%8c%96%e5%ad%a6%e6%a7%8b%e9%80%a0%e3%81%ab%e3%82%88%e3%82%8b%e5%a4%89%e7%95%b0%e5%8e%9f%e6%80%a7%e4%ba%88%e6%b8%ac%ef%bc%92","status":"publish","type":"post","link":"https:\/\/u-lab2.my-pharm.ac.jp\/~mminfo\/blog\/2717\/","title":{"rendered":"\u5316\u5b66\u69cb\u9020\u306b\u3088\u308b\u5909\u7570\u539f\u6027\u4e88\u6e2c\uff12\uff1aQSAR\u3068\u30eb\u30fc\u30eb\u30d9\u30fc\u30b9\u4e88\u6e2c\u30b7\u30b9\u30c6\u30e0"},"content":{"rendered":"

\u5316\u5b66\u69cb\u9020\u306b\u3088\u308b\u5909\u7570\u539f\u6027\u4e88\u6e2c\u306b\u95a2\u3059\u308b\u30b3\u30f3\u30da\u30c6\u30a3\u30b7\u30e7\u30f3\u306f
\n \u300cAmes\/QSAR International Challenge Project<\/span>\u300d<\/span><\/strong>
\n \u3068\u8a00\u3044\u307e\u3059\u3002
\n \u307e\u305a\u306f\u3053\u306e\u30b3\u30f3\u30da\u304c\u3069\u3093\u306a\u3082\u306e\u306a\u306e\u304b\u3092\u30bf\u30a4\u30c8\u30eb\u304b\u3089\u7d10\u89e3\u3044\u3066\u884c\u304d\u307e\u3057\u3087\u3046\u3002<\/p>\n

 <\/p>\n

\u6700\u521d\u306bAmes\/QSAR<\/span><\/strong><\/span>\u3068\u3042\u308a\u307e\u3059\u3002
\n \u3053\u308c\u306f\u3001Ames\u8a66\u9a13\u306e\u7d50\u679c\u3092QSAR\u89e3\u6790\u3067\u4e88\u6e2c\u3059\u308b\u3068\u3044\u3063\u305f\u610f\u5473\u3067\u3059\u3002<\/p>\n

International Challenge<\/span><\/strong><\/span>\u306f\u56fd\u969b\u7684\u306a\u30b3\u30f3\u30da\u30c6\u30a3\u30b7\u30e7\u30f3\u3068\u3044\u3046\u3053\u3068\u3067\u3059\u306d\u3002<\/p>\n

 <\/p>\n

Ames\u8a66\u9a13<\/span><\/strong><\/span>\u306f\u3001\u5316\u5b66\u7269\u8cea\u304c\u5909\u7570\u539f\u6027<\/span><\/strong>\u3092\u6301\u3064\u304b\u3069\u3046\u304b\u3092\u8a55\u4fa1\u3059\u308b\u305f\u3081\u306e\u5b9f\u9a13\u7684\u624b\u6cd5\u3067\u3059\u3002
\n \u3053\u306e\u8a66\u9a13\u306f\u7d30\u83cc\u3092\u4f7f\u7528\u3057\u3001\u7279\u5b9a\u306e\u682a\uff08\u901a\u5e38\u306f\u30b5\u30eb\u30e2\u30cd\u30e9\u5c5e\uff09\u306b\u5316\u5b66\u7269\u8cea\u3092\u66dd\u9732\u3059\u308b\u3053\u3068\u3067\u3001\u305d\u306e\u7269\u8cea\u304cDNA\u306b\u5909\u7570\u3092\u5f15\u304d\u8d77\u3053\u3059\u80fd\u529b<\/span><\/strong>\u3092\u8abf\u3079\u307e\u3059\u3002
\n \u5909\u7570\u539f\u6027\u304c\u3042\u308b\u3068\u8003\u3048\u3089\u308c\u308b\u5316\u5b66\u7269\u8cea\u306f\u3001\u304c\u3093<\/span><\/strong>\u3084\u4ed6\u306e\u907a\u4f1d\u7684\u75be\u60a3<\/strong><\/span>\u306e\u30ea\u30b9\u30af\u3092\u9ad8\u3081\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u305f\u3081\u3001Ames\u8a66\u9a13\u306f\u5316\u5b66\u7269\u8cea\u306e\u5b89\u5168\u6027\u8a55\u4fa1\u306b\u304a\u3044\u3066\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n

 <\/p>\n

\u4e00\u65b9\u3001QSAR<\/span><\/strong>\uff08\u30ad\u30e5\u30fc\u30b5\u30fc\uff09\u3068\u3044\u3046\u306e\u306f\u5b9a\u91cf\u7684\u69cb\u9020\u6d3b\u6027\u76f8\u95a2<\/span><\/strong>\uff08Quantitative Structure-Activity Relationship\uff09\u306e\u7565\u79f0\u3067\u3059\u3002
\n QSAR\u89e3\u6790\u306f\u3001\u5316\u5b66\u7269\u8cea\u306e\u69cb\u9020<\/span><\/strong>\u3068\u751f\u7406\u6d3b\u6027<\/span><\/strong>\u3068\u306e\u95a2\u4fc2\u304b\u3089\u4e88\u6e2c\u30e2\u30c7\u30eb<\/span><\/strong>\u3092\u4f5c\u308b\u65b9\u6cd5\u3067\u3059\u3002
\n Ames\u8a66\u9a13\u306e\u4e88\u6e2c\u6cd5\u306f\u5927\u304d\u304f\u7d71\u8a08\u30d9\u30fc\u30b9\u3068\u77e5\u8b58\u30d9\u30fc\u30b9\u306e\u4e8c\u3064\u306b\u5206\u985e\u3055\u308c\u307e\u3059\u3002<\/p>\n

 <\/p>\n

\u7d71\u8a08\u30d9\u30fc\u30b9\uff08QSAR\u30b7\u30b9\u30c6\u30e0\uff09<\/span><\/strong>:<\/strong><\/span>
\n \u5316\u5408\u7269\u30c7\u30fc\u30bf\u30bb\u30c3\u30c8\u304b\u3089\u69cb\u9020\u3068\u751f\u7406\u6d3b\u6027\u306e\u9593\u306e\u30d1\u30bf\u30fc\u30f3\u3092\u898b\u3064\u3051\u307e\u3059\u3002<\/span>
\n \u6a5f\u68b0\u5b66\u7fd2\u3084\u7d71\u8a08\u7684\u624b\u6cd5\u306b\u3088\u3063\u3066\u3001\u5316\u5b66\u69cb\u9020\u3068\u6d3b\u6027\u306e\u9593\u306e\u91cf\u7684\u95a2\u4fc2\u3092\u30e2\u30c7\u30eb\u5316\uff08\u6570\u5f0f\u5316\uff09\u3057\u307e\u3059\u3002<\/span><\/p>\n

\uff08\u5f53\u7814\u7a76\u5ba4\u3067\u306f\u3053\u3061\u3089\u3092\u5f97\u610f\u3068\u3057\u3066\u3044\u307e\u3059\u3002\uff09<\/p>\n

\u77e5\u8b58\u30d9\u30fc\u30b9\uff08\u30eb\u30fc\u30eb\u30d9\u30fc\u30b9\u30fb\u30a8\u30ad\u30b9\u30d1\u30fc\u30c8\u30b7\u30b9\u30c6\u30e0\uff09<\/span>:<\/strong><\/span>
\n \u3053\u306e\u624b\u6cd5\u3067\u306f\u3001\u7279\u5b9a\u306e\u5b98\u80fd\u57fa\u3084\u69cb\u9020\u7684\u7279\u5fb4\u304c\u751f\u7406\u6d3b\u6027\u306b\u4e0e\u3048\u308b\u5f71\u97ff\u3092\u4eca\u307e\u3067\u306b\u84c4\u3048\u3089\u308c\u305f\u77e5\u8b58\u306b\u57fa\u3065\u3044\u3066\u4e88\u6e2c\u3057\u307e\u3059\u3002<\/span><\/p>\n

QSAR\u306b\u5bfe\u3057\u3066SAR\uff08\u69cb\u9020\u6d3b\u6027\u76f8\u95a2\uff09<\/span><\/strong>\u3068\u3057\u3066\u533a\u5225\u3055\u308c\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/span><\/p>\n

\u7d71\u8a08\u30d9\u30fc\u30b9\u304a\u3088\u3073\u77e5\u8b58\u30d9\u30fc\u30b9\u306e\u4e88\u6e2c\u6cd5\u3092ICH\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u3067\u306f(Q)SAR<\/span><\/strong><\/a>\u3068\u8868\u73fe\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n

 <\/p>\n

\u30b3\u30f3\u30da\u3067\u306f\u3053\u308c\u3089\u306e\u4e21\u65b9\u306e\u89e3\u6790\u30a2\u30d7\u30ed\u30fc\u30c1\u3092\u4f7f\u7528\u3057\u305f\u591a\u69d8\u306a\u30e2\u30c7\u30eb\u304c\u6295\u5165\u3055\u308c\u3001\u305d\u306e\u4e88\u6e2c\u6027\u80fd\u3092\u7af6\u3044\u307e\u3057\u305f\u3002<\/p>\n

 <\/p>\n

\u306a\u304a\u3001\u3053\u306e\u30b3\u30f3\u30da\u306f1st\u30d7\u30ed\u30b8\u30a7\u30af\u30c8\uff082014\u5e74\uff5e2017\u5e74\uff09<\/span>\u30682nd\u30d7\u30ed\u30b8\u30a7\u30af\u30c8\uff082020\u5e74\uff5e2022\u5e74\uff09\u306e\u4e8c\u56de\u5b9f\u65bd\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n

1st\u30d7\u30ed\u30b8\u30a7\u30af\u30c8\u3067\u306fQSAR\u89e3\u6790\u30bd\u30d5\u30c8\u306e\u958b\u767a\u3092\u624b\u304c\u3051\u3066\u3044\u308b\u4f01\u696d\u306e\u307f\u304c\u53c2\u52a0\u3057\u307e\u3057\u305f\u3002<\/p>\n

\u79c1\u305f\u3061\u304c\u53c2\u52a0\u3057\u305f\u306e\u306f\u3001\u30a2\u30ab\u30c7\u30df\u30a2\uff08\u5927\u5b66\u3084\u7814\u7a76\u6240\uff09\u306b\u3082\u9580\u6238\u304c\u958b\u304b\u308c\u305f2nd\u30d7\u30ed\u30b8\u30a7\u30af\u30c8\u306e\u65b9\u3067\u3059\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

\u5316\u5b66\u69cb\u9020\u306b\u3088\u308b\u5909\u7570\u539f\u6027\u4e88\u6e2c\u306b\u95a2\u3059\u308b\u30b3\u30f3\u30da\u30c6\u30a3\u30b7\u30e7\u30f3\u306f \u300cAmes\/QSAR International Challenge Project\u300d \u3068\u8a00\u3044\u307e\u3059\u3002 \u307e\u305a\u306f\u3053\u306e\u30b3\u30f3\u30da\u304c\u3069\u3093\u306a\u3082\u306e\u306a\u306e\u304b\u3092\u30bf\u30a4\u30c8\u30eb\u304b\u3089\u7d10\u89e3\u3044\u3066\u884c\u304d\u307e\u3057 […]<\/p>\n","protected":false},"author":11,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"vkexunit_cta_each_option":"","footnotes":""},"categories":[18],"tags":[20,21],"class_list":["post-2717","post","type-post","status-publish","format-standard","hentry","category-blog","tag-ames","tag-qsar"],"_links":{"self":[{"href":"https:\/\/u-lab2.my-pharm.ac.jp\/~mminfo\/wp-json\/wp\/v2\/posts\/2717","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/u-lab2.my-pharm.ac.jp\/~mminfo\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/u-lab2.my-pharm.ac.jp\/~mminfo\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/u-lab2.my-pharm.ac.jp\/~mminfo\/wp-json\/wp\/v2\/users\/11"}],"replies":[{"embeddable":true,"href":"https:\/\/u-lab2.my-pharm.ac.jp\/~mminfo\/wp-json\/wp\/v2\/comments?post=2717"}],"version-history":[{"count":0,"href":"https:\/\/u-lab2.my-pharm.ac.jp\/~mminfo\/wp-json\/wp\/v2\/posts\/2717\/revisions"}],"wp:attachment":[{"href":"https:\/\/u-lab2.my-pharm.ac.jp\/~mminfo\/wp-json\/wp\/v2\/media?parent=2717"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/u-lab2.my-pharm.ac.jp\/~mminfo\/wp-json\/wp\/v2\/categories?post=2717"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/u-lab2.my-pharm.ac.jp\/~mminfo\/wp-json\/wp\/v2\/tags?post=2717"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}