{"id":2737,"date":"2023-12-31T19:28:55","date_gmt":"2023-12-31T10:28:55","guid":{"rendered":"https:\/\/u-lab.my-pharm.ac.jp\/~mminfo\/?p=2737"},"modified":"2023-12-31T19:28:55","modified_gmt":"2023-12-31T10:28:55","slug":"%e5%8c%96%e5%ad%a6%e6%a7%8b%e9%80%a0%e3%81%ab%e3%82%88%e3%82%8b%e5%a4%89%e7%95%b0%e5%8e%9f%e6%80%a7%e4%ba%88%e6%b8%ac%ef%bc%96","status":"publish","type":"post","link":"https:\/\/u-lab2.my-pharm.ac.jp\/~mminfo\/blog\/2737\/","title":{"rendered":"\u5316\u5b66\u69cb\u9020\u306b\u3088\u308b\u5909\u7570\u539f\u6027\u4e88\u6e2c\uff16\uff1a\u8a55\u4fa1\u6307\u6a19\uff08\u6b63\u78ba\u5ea6\uff09"},"content":{"rendered":"

Ames\/QSAR\u56fd\u969b\u30c1\u30e3\u30ec\u30f3\u30b8<\/a>\u3067\u306f\u4e88\u6e2c\u30e2\u30c7\u30eb\u306e\u6027\u80fd\u3092\u591a\u89d2\u7684\u306b\u8a55\u4fa1\u3057\u3066\u3044\u307e\u3059\u3002
\n \u4eca\u56de\u306f\u3001\u3053\u306e\u300c\u8a55\u4fa1\u6307\u6a19\u300d<\/strong><\/span>\u306e\u5c0e\u5165\u90e8\u5206\u306b\u3064\u3044\u3066\u8ff0\u3079\u3066\u3044\u304d\u307e\u3059\u3002<\/p>\n

 <\/p>\n

\u3053\u306e\u30b3\u30f3\u30da\u3067\u306f\u3001\u5404\u30c1\u30fc\u30e0\u304c\u69cb\u7bc9\u3057\u305f\u8b58\u5225\u30e2\u30c7\u30eb\u3067Ames\u8a66\u9a13\u306e\u967d\u6027\u30fb\u9670\u6027\u3092\u4e88\u6e2c\u3057\u3066\u3044\u307e\u3059\u3002
\n \u30d6\u30e9\u30a4\u30f3\u30c9\u30c6\u30b9\u30c8\u30bb\u30c3\u30c8\u5316\u5408\u7269\u306e\u4e88\u6e2c\u3068\u3044\u3046\u306e\u306f\u96e3\u3057\u3044\u3067\u3059\u306e\u3067\u3001\u5f53\u305f\u3063\u305f\u308a\u5916\u308c\u305f\u308a\u3057\u307e\u3059\u3002
\n \u3064\u307e\u308a\u3001\u4e88\u6e2c\u306e\u7d50\u679c\u306f\u6b21\u306e\u3088\u3046\u306a\uff14\u30d1\u30bf\u30fc\u30f3\u306b\u5206\u985e\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n\n\n
\u00a0<\/strong><\/span><\/td>\n\u4e88\u6e2c\u5024\u967d\u6027<\/span><\/strong><\/span><\/td>\n\u4e88\u6e2c\u5024\u9670\u6027<\/span><\/strong><\/span><\/td>\n<\/tr>\n
\u5b9f\u6e2c\u5024\u967d\u6027<\/span><\/strong><\/span><\/td>\nTP<\/strong><\/span><\/td>\nFN<\/strong><\/span><\/td>\n<\/tr>\n
\u5b9f\u6e2c\u5024\u9670\u6027<\/span><\/strong><\/span><\/td>\nFP<\/strong><\/span><\/td>\nTN<\/strong><\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u4e88\u6e2c\u7d50\u679c\u304c\u967d\u6027\u3067\u3001\u7b54\u3048\u3082\u967d\u6027\uff1a\u3053\u306e\u30d1\u30bf\u30fc\u30f3\u3092\u771f\u967d\u6027<\/span><\/strong>\uff08True Positive\uff1aTP<\/span><\/strong>\uff09\u3068\u8a00\u3044\u307e\u3059\u3002\u5f53\u305f\u3063\u3066\u307e\u3059\u3002
\n \u4e88\u6e2c\u7d50\u679c\u304c\u9670\u6027\u3067\u3001\u7b54\u3048\u3082\u9670\u6027\uff1a\u3053\u306e\u30d1\u30bf\u30fc\u30f3\u3092\u771f\u9670\u6027<\/span><\/strong>\uff08True Negative\uff1aTN<\/span><\/strong>\uff09\u3068\u8a00\u3044\u307e\u3059\u3002\u3053\u308c\u3082\u5f53\u305f\u3063\u3066\u307e\u3059\u3002
\n \u4e88\u6e2c\u7d50\u679c\u304c\u967d\u6027\u3067\u3001\u7b54\u3048\u306f\u9670\u6027\uff1a\u3053\u306e\u30d1\u30bf\u30fc\u30f3\u3092\u507d\u967d\u6027<\/strong><\/span>\uff08False Positive\uff1aFP<\/span><\/strong>\uff09\u3068\u8a00\u3044\u307e\u3059\u3002\u5916\u308c\u3066\u307e\u3059\u3002
\n \u4e88\u6e2c\u7d50\u679c\u304c\u9670\u6027\u3067\u3001\u7b54\u3048\u306f\u967d\u6027\uff1a\u3053\u306e\u30d1\u30bf\u30fc\u30f3\u3092\u507d\u9670\u6027<\/span><\/strong>\uff08False Negative\uff1aFN<\/span><\/strong>\uff09\u3068\u8a00\u3044\u307e\u3059\u3002\u5916\u308c\u3066\u307e\u3059\u3002<\/p>\n

 <\/p>\n

 <\/p>\n

\u8981\u3059\u308b\u306b\u3001\u6b63\u89e3\u3067\u3042\u308b\u771f\u967d\u6027\u3068\u771f\u9670\u6027\u306e\u5316\u5408\u7269\u306e\u6570\uff08TP + TN\uff09<\/span><\/strong>\u304c\u591a\u3051\u308c\u3070\u4e88\u6e2c\u30e2\u30c7\u30eb\u306e\u6027\u80fd\u304c\u826f\u304b\u3063\u305f\u3001\u3068\u8a00\u3048\u305d\u3046\u3067\u3059\u3002
\n \u30c6\u30b9\u30c8\u306b\u4f7f\u308f\u308c\u305f\u5168\u3066\u306e\u5316\u5408\u7269\u6570\u306b\u5bfe\u3059\u308b\u6b63\u89e3\u306e\u6570\u306e\u5272\u5408\u3092\u6b63\u78ba<\/strong><\/span>\u5ea6\uff08Accuracy: Acc\uff09<\/span><\/strong><\/span>\u3068\u8a00\u3044\u3001\u6027\u80fd\u8a55\u4fa1\u306e\u91cd\u8981\u306a\u6307\u6a19\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002
\n \u6b63\u78ba\u5ea6\u306f\u6b21\u306e\u3088\u3046\u306a\u308f\u304b\u308a\u3084\u3059\u3044\u5f0f\u3067\u5b9a\u7fa9\u3055\u308c\u307e\u3059\u3002<\/p>\n

 <\/p>\n

Acc=\uff08TP+TN\uff09\/\uff08TP+TN+FP+FN\uff09<\/span><\/strong><\/span><\/p>\n

 <\/p>\n

\u6b63\u78ba\u5ea6\u306f\u3068\u3066\u3082\u308f\u304b\u308a\u3084\u3059\u3044\u306e\u3067\u69d8\u3005\u306a\u3068\u3053\u308d\u3067\u4e88\u6e2c\u30e2\u30c7\u30eb\u306e\u8a55\u4fa1\u57fa\u6e96\u306b\u4f7f\u7528\u3055\u308c\u3066\u3044\u307e\u3059\u3002
\n \u3067\u3082\u5b9f\u306f\u3053\u306e\u8a55\u4fa1\u6307\u6a19\u306e\u4f7f\u7528\u306b\u306f\u6ce8\u610f\u304c\u5fc5\u8981<\/strong><\/span>\u306a\u5834\u5408\u304c\u3042\u308a\u307e\u3059\u3002
\n \u305d\u308c\u306f\u3001\u4e88\u6e2c\u3059\u308b\u5316\u5408\u7269\u306b\u304a\u3051\u308b\u967d\u6027\u3068\u9670\u6027\u306e\u5272\u5408\u304c\u6975\u7aef\u306b\u504f\u3063\u3066\u3044\u308b\u3068\u304d<\/span><\/strong>\u3067\u3059\u3002
\n \u3053\u306e\u3088\u3046\u306a\u30b5\u30f3\u30d7\u30eb\u3092\u4e0d\u5747\u8861\uff08imbalance\uff09\u306a\u30b5\u30f3\u30d7\u30eb<\/strong><\/span>\u306a\u3069\u3068\u547c\u3073\u307e\u3059\u3002<\/p>\n

\n \u4f8b\u3048\u3070\u3001\u967d\u6027\u5316\u5408\u7269\u304c1000\u500b\u4e2d\u306b10\u500b\u3057\u304b\u542b\u307e\u308c\u3066\u3044\u306a\u3044\u6975\u7aef\u306b\u30a4\u30f3\u30d0\u30e9\u30f3\u30b9\u306a\u5316\u5408\u7269\u30bb\u30c3\u30c8\u304c\u6709\u3063\u305f\u3068\u3057\u307e\u3059\u3002
\n \u4e88\u6e2c\u30e2\u30c7\u30eb\u304c\u4e88\u6e2c\u3092\u5168\u304f\u3057\u306a\u3044\u3067\u3001\u3069\u3093\u306a\u5316\u5408\u7269\u306b\u5bfe\u3057\u3066\u3082\u3068\u308a\u3042\u3048\u305a\u5168\u90e8\u9670\u6027\u3001\u3068\u5224\u5b9a\u3059\u308b\u3088\u3046\u306a\u51fa\u6765\u640d\u306a\u3044\u3060\u3063\u305f\u3068\u3057\u3066\u3082\u3001<\/p>\n

 <\/p>\n

TP=0
\n TN=990
\n FP=10
\n FN=0<\/p>\n

 <\/p>\n

\u3068\u306a\u3063\u3066\u3001<\/p>\n

 <\/p>\n

Acc=(0+990)\/1000=99%<\/p>\n

\n \u3068\u3044\u3046\u3001\u3042\u305f\u304b\u3082\u6b63\u78ba\u5ea6\u304c\u826f\u597d\u306a\u4e88\u6e2c\u6027\u80fd\u3092\u5099\u3048\u305f\u30e2\u30c7\u30eb\u304c\u3067\u304d\u305f\u3068\u52d8\u9055\u3044<\/span><\/strong>\u3057\u3066\u3057\u307e\u3044\u307e\u3059\u3002<\/p>\n

\u3082\u3061\u308d\u3093\u3053\u306e\u7d50\u8ad6\u306f\u8aa4\u308a\u3067\u3042\u3063\u3066\u3001\u967d\u6027\u306e10\u5316\u5408\u7269\u3092\u3067\u304d\u308b\u3060\u3051\u6b63\u3057\u304f\u4e88\u6e2c\u3067\u304d\u306a\u3051\u308c\u3070\u826f\u3044\u4e88\u6e2c\u30e2\u30c7\u30eb\u3068\u306f\u8a00\u3048\u307e\u305b\u3093<\/span><\/strong>\u3002<\/p>\n

 <\/p>\n

\u5b9f\u969b\u306eAmes\u8a66\u9a13\u306e\u7d50\u679c\u306f\u3053\u3053\u307e\u3067\u6975\u7aef\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u304c\u3001\u3084\u306f\u308a<\/span>\u4e0d\u5747\u8861<\/strong><\/span>\u3067\u3059\u3002
\n Ames\/QSAR\u56fd\u969b\u30c1\u30e3\u30ec\u30f3\u30b8\u306e\u30c7\u30fc\u30bf\u3067\u3059\u3068\u3001\uff11\uff15\uff05\u304f\u3089\u3044\u304c\u967d\u6027\u3001\uff18\uff15\uff05\u304f\u3089\u3044\u304c\u9670\u6027\u3067\u3059\u3002
\n \u3068\u308a\u3042\u3048\u305a\u5168\u90e8\u9670\u6027\u3068\u7b54\u3048\u308b\u30c0\u30e1\u306a\u30e2\u30c7\u30eb\u3092\u63d0\u51fa\u3057\u305f\u3068\u3057\u3066\u3082\u3001\u6b63\u78ba\u5ea6\uff18\uff15\uff05\u306e\u304b\u306a\u308a\u826f\u3044\u90e8\u985e\u306e\u30e2\u30c7\u30eb\u304c\u69cb\u7bc9\u3067\u304d\u305f\u3053\u3068\u306b\u306a\u3063\u3066\u3057\u307e\u3044\u307e\u3059\u3002<\/p>\n

\u3053\u306e\u3088\u3046\u306b\u3001\u6b63\u78ba\u5ea6\u306f\u76f4\u611f\u7684\u306b\u308f\u304b\u308a\u3084\u3059\u304f\u3066\u4fbf\u5229\u306a\u8a55\u4fa1\u6307\u6a19\u306a\u306e\u3067\u3059\u304c\u3001\u4e0d\u5747\u8861\u306a\u30c7\u30fc\u30bf\u306b\u9069\u7528\u3059\u308b\u969b\u306b\u306f\u4ed6\u306e\u69d8\u3005\u306a\u8a55\u4fa1\u6307\u6a19\u3068\u7d44\u307f\u5408\u308f\u305b\u306a\u3044\u3068\u8aa4\u3063\u305f\u7d50\u8ad6\u3092\u5c0e\u3044\u3066\u3057\u307e\u3046\u305f\u3081\u306b\u6ce8\u610f\u304c\u5fc5\u8981\u3067\u3059\u3002<\/p>\n

\n \u8b58\u5225\u30e2\u30c7\u30eb\u306e\u69d8\u3005\u306a\u8a55\u4fa1\u6307\u6a19\u306f\u57fa\u672c\u7684\u306bTP\u3001TN\u3001FP\u3001FN<\/span><\/strong>\u306e\uff14\u3064\u306e\u5316\u5408\u7269\u6570\u304b\u3089\u8a08\u7b97\u3055\u308c\u308b\u306e\u3067\u3059\u304c\u3001\u306a\u304b\u306a\u304b\u5965\u6df1\u3044\u3082\u306e\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

Ames\/QSAR\u56fd\u969b\u30c1\u30e3\u30ec\u30f3\u30b8\u3067\u306f\u4e88\u6e2c\u30e2\u30c7\u30eb\u306e\u6027\u80fd\u3092\u591a\u89d2\u7684\u306b\u8a55\u4fa1\u3057\u3066\u3044\u307e\u3059\u3002 \u4eca\u56de\u306f\u3001\u3053\u306e\u300c\u8a55\u4fa1\u6307\u6a19\u300d\u306e\u5c0e\u5165\u90e8\u5206\u306b\u3064\u3044\u3066\u8ff0\u3079\u3066\u3044\u304d\u307e\u3059\u3002   \u3053\u306e\u30b3\u30f3\u30da\u3067\u306f\u3001\u5404\u30c1\u30fc\u30e0\u304c\u69cb\u7bc9\u3057\u305f\u8b58\u5225\u30e2\u30c7\u30eb\u3067Ames\u8a66\u9a13\u306e\u967d\u6027\u30fb […]<\/p>\n","protected":false},"author":11,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"vkexunit_cta_each_option":"","footnotes":""},"categories":[18],"tags":[20,21],"class_list":["post-2737","post","type-post","status-publish","format-standard","hentry","category-blog","tag-ames","tag-qsar"],"_links":{"self":[{"href":"https:\/\/u-lab2.my-pharm.ac.jp\/~mminfo\/wp-json\/wp\/v2\/posts\/2737","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/u-lab2.my-pharm.ac.jp\/~mminfo\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/u-lab2.my-pharm.ac.jp\/~mminfo\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/u-lab2.my-pharm.ac.jp\/~mminfo\/wp-json\/wp\/v2\/users\/11"}],"replies":[{"embeddable":true,"href":"https:\/\/u-lab2.my-pharm.ac.jp\/~mminfo\/wp-json\/wp\/v2\/comments?post=2737"}],"version-history":[{"count":0,"href":"https:\/\/u-lab2.my-pharm.ac.jp\/~mminfo\/wp-json\/wp\/v2\/posts\/2737\/revisions"}],"wp:attachment":[{"href":"https:\/\/u-lab2.my-pharm.ac.jp\/~mminfo\/wp-json\/wp\/v2\/media?parent=2737"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/u-lab2.my-pharm.ac.jp\/~mminfo\/wp-json\/wp\/v2\/categories?post=2737"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/u-lab2.my-pharm.ac.jp\/~mminfo\/wp-json\/wp\/v2\/tags?post=2737"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}