{"id":2948,"date":"2024-01-16T13:15:19","date_gmt":"2024-01-16T04:15:19","guid":{"rendered":"https:\/\/u-lab.my-pharm.ac.jp\/~mminfo\/?p=2948"},"modified":"2024-01-16T13:15:19","modified_gmt":"2024-01-16T04:15:19","slug":"%e5%8c%96%e5%ad%a6%e6%a7%8b%e9%80%a0%e3%81%ab%e3%82%88%e3%82%8b%e5%a4%89%e7%95%b0%e5%8e%9f%e6%80%a7%e4%ba%88%e6%b8%ac%ef%bc%914%ef%bc%9a%e4%b8%8a%e4%bd%8d%e3%81%ae%e4%ba%88%e6%b8%ac%e3%83%a2%e3%83%87","status":"publish","type":"post","link":"https:\/\/u-lab2.my-pharm.ac.jp\/~mminfo\/blog\/2948\/","title":{"rendered":"\u5316\u5b66\u69cb\u9020\u306b\u3088\u308b\u5909\u7570\u539f\u6027\u4e88\u6e2c\uff11\uff15\uff1a\u4e0a\u4f4d\u306e\u4e88\u6e2c\u30e2\u30c7\u30eb\u306e\u6982\u8981"},"content":{"rendered":"

\u7b2c1\u56de<\/a>\u304a\u3088\u3073\u7b2c2\u56de<\/a>Ames\/QSAR\u56fd\u969b\u30c1\u30e3\u30ec\u30f3\u30b8\u30d7\u30ed\u30b8\u30a7\u30af\u30c8\u306b\u63d0\u51fa\u3055\u308c\u305f\u5168109\u30e2\u30c7\u30eb\u3092\u7cbe\u67fb\u3057\u305f\u7d50\u679c\u3001\u5168\u30c6\u30b9\u30c8\u5316\u5408\u7269\u3092\u4e88\u6e2c\u3057\u305f\uff08\u30ab\u30d0\u30fc\u7387100%\uff09\u3068\u4eee\u5b9a\u3057\u305f\u3068\u304d\u306e\u6700\u826f\u306e\u4e88\u6e2c\u30e2\u30c7\u30eb\u306f\u3001\u660e\u6cbb\u85ac\u79d1\u5927\u5b66\u306eMMI-STK1\u3067\u3042\u308b\u3068\u63a8\u5b9a\u3055\u308c\u307e\u3057\u305f<\/a>\u3002<\/p>\n

\n \u7d71\u5408\u7684\u8a55\u4fa1\u6307\u6a19\uff08PC1)\u306e\u9806\u306b\u4e0a\u4f4d\u30e2\u30c7\u30eb\u3092\u518d\u63b2\u3059\u308b\u3068\u3001
\n 1\u4f4d\uff1a\u660e\u6cbb\u85ac\u79d1\u5927\u5b66\u306eMMI-STK1<\/strong><\/span>
\n 2\u4f4d\uff1a\u660e\u6cbb\u85ac\u79d1\u5927\u5b66\u306eMMI-VOTE1<\/strong><\/span>
\n 3\u4f4d\uff1a\u660e\u6cbb\u85ac\u79d1\u5927\u5b66\u306eMMI-STK2<\/strong><\/span>
\n 4\u4f4d\uff1a\u660e\u6cbb\u85ac\u79d1\u5927\u5b66\u306eMMI-VOTE2<\/strong><\/span>
\n 5\u4f4d\uff1aMultiCASE\u793e\u306eBM PHARMA<\/strong><\/span>
\n 6\u4f4d\uff1aLharsa\u793e\u306eDerec Nexus<\/strong><\/span>
\n \u3068\u306a\u308a\u307e\u3059\u3002
\n \u4eca\u56de\u306f\u3053\u308c\u3089\u306e\u4e88\u6e2c\u30e2\u30c7\u30eb\u304c\u3069\u3093\u306a\u3082\u306e\u306a\u306e\u304b\u3092\u3001\u4e3b\u50ac\u8005\u306e\u5831\u544a\u8ad6\u6587\u304b\u3089\u629c\u7c8b\u3057\u3066\u304a\u793a\u3057\u3057\u307e\u3059\u3002<\/p>\n

 <\/p>\n

1\u4f4d\u306eMMI-STK1\uff08\u660e\u6cbb\u85ac\u79d1\u5927\u5b66\uff09<\/span><\/strong>\u306f\u3001\u7b2c2\u56de\u30c1\u30e3\u30ec\u30f3\u30b8\u3067\u79c1\u305f\u3061\uff08\u9ed2\u5d0e\u3001\u4f50\u3005\u6728\u3001\u677e\u5742\u3001\u690d\u6ca2\uff09\u304c\u63d0\u51fa\u3057\u305f\u7d71\u8a08\u30d9\u30fc\u30b9\u306e\u4e88\u6e2c\u30e2\u30c7\u30eb\u3067\u3059\u3002
\n \u79c1\u305f\u3061\u306f\u5f8c\u8ff0\u3059\u308bMMI-STK2\u3068MMI-VOTE2\u3092\u8a55\u4fa1\u7528\u30e2\u30c7\u30eb\u3068\u3057\u3066\u9078\u629e\u3057\u307e\u3057\u305f\u306e\u3067\u3001\u3053\u306e\u30e2\u30c7\u30eb\u306f\u8ad6\u6587\u306e\u672c\u6587\u306b\u306f\u767b\u5834\u3057\u3066\u3044\u307e\u305b\u3093\u3002\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u30c7\u30fc\u30bf<\/a>\u306e\u4e2d\u306b\u30e2\u30c7\u30eb\u306e\u6982\u8981\u3068\u8a55\u4fa1\u5024\u304c\u8a18\u8f09\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

MMI-STK1\u306e\u69cb\u7bc9\u306b\u4f7f\u7528\u3057\u305f\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u30c7\u30fc\u30bf\u306f\u4e3b\u50ac\u8005\u304c\u914d\u5e03\u3057\u305f\u7b2c1\u56de\u30c1\u30e3\u30ec\u30f3\u30b8\u306b\u304a\u3051\u308bPhase1,2,3\u306e\u30c7\u30fc\u30bf\u306e\u307f\u3067\u3059\u3002\u305d\u306e\u307b\u304b\u306e\u5916\u90e8\u30c7\u30fc\u30bf\u306f\u4e00\u5207\u4f7f\u7528\u3057\u3066\u3044\u307e\u305b\u3093\u3002
\n \u3053\u308c\u3089\u306e\u5206\u5b50\u69cb\u9020\u304b\u3089\u5316\u5b66\u69cb\u9020\u8a18\u8ff0\u5b50\u3092\u7b97\u51fa\u3057\u3066\u6a5f\u68b0\u5b66\u7fd2\u306b\u4f9b\u3057\u307e\u3057\u305f\u3002
\n \u8a18\u8ff0\u5b50\u306e\u7b97\u5b9a\u306b\u4f7f\u7528\u3057\u305f\u30a2\u30d7\u30ea\u30b1\u30fc\u30b7\u30e7\u30f3\u306f\u3001Dragon\u3001MOE\u3001Mordred<\/span><\/strong>\u3067\u3059\u3002
\n \u307e\u305f\u3001\u6a5f\u68b0\u5b66\u7fd2\u5668\u306b\u306f\u6c7a\u5b9a\u6728\u7cfb\u306eLight GBM\u3001XG-Boost<\/span><\/strong>\u3068\u3068\u3082\u306bGraph Convolutional Network<\/span><\/strong>\u3092\u4f7f\u7528\u3057\u3066\u3044\u307e\u3059\u3002
\n \u3053\u308c\u3089\u306e\u6a5f\u68b0\u5b66\u7fd2\u5668\u3092\u30b9\u30bf\u30c3\u30ad\u30f3\u30b0<\/span><\/strong>\u3059\u308b\u3053\u3068\u306b\u3088\u3063\u3066\u6700\u7d42\u7d50\u679c\u3092\u51fa\u529b\u3057\u307e\u3057\u305f\u3002<\/p>\n

 <\/p>\n

2\u4f4d\u306eMMI-VOTE1\uff08\u660e\u6cbb\u85ac\u79d1\u5927\u5b66\uff09<\/span><\/strong>\u3082\u3001\u7b2c2\u56de\u30c1\u30e3\u30ec\u30f3\u30b8\u3067\u79c1\u305f\u3061\u304c\u63d0\u51fa\u3057\u305f\u7d71\u8a08\u30d9\u30fc\u30b9\u306e\u4e88\u6e2c\u30e2\u30c7\u30eb\u3067\u3059\u3002\u3084\u306f\u308a\u3001\u8ad6\u6587\u672c\u6587\u3067\u306f\u767b\u5834\u3057\u3066\u3044\u307e\u305b\u3093\u3002
\n \u3053\u306e\u30e2\u30c7\u30eb\u306e\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u30bb\u30c3\u30c8\u3082\u4e3b\u50ac\u8005\u304c\u914d\u5e03\u3057\u305f\u7b2c1\u56de\u30c1\u30e3\u30ec\u30f3\u30b8\u306b\u304a\u3051\u308bPhase1,2,3\u306e\u30c7\u30fc\u30bf\u306e\u307f\u3067\u3059\u3002
\n \u3053\u306e\u30e2\u30c7\u30eb\u306f\u3001Dragon\u3001MOE\u3001Mordred<\/span><\/strong>\u304b\u3089\u306a\u308b\u591a\u69d8\u306a\u8a18\u8ff0\u5b50\u3068Light GBM\u3001XG-Boost\u3001Deep Learning\u3001Graph Convolutional Network<\/span><\/strong>\u3068\u3044\u3063\u305f\u591a\u69d8\u306a\u6a5f\u68b0\u5b66\u7fd2\u5668\u3092\u7528\u3044\u306699\u7a2e\u985e\u306e\u30b9\u30bf\u30c3\u30ad\u30f3\u30b0\u30e2\u30c7\u30eb<\/span><\/strong>\u3092\u69cb\u7bc9\u3057\u3001\u6700\u7d42\u7d50\u679c\u3092\u591a\u6570\u6c7a<\/span><\/strong>\u306b\u3088\u3063\u3066\u6c7a\u5b9a\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n

 <\/p>\n

3\u4f4d\u306eMMI-STK2\uff08\u660e\u6cbb\u85ac\u79d1\u5927\u5b66\uff09<\/span><\/strong>\u3082\u3001\u7b2c2\u56de\u30c1\u30e3\u30ec\u30f3\u30b8\u3067\u79c1\u305f\u3061\u304c\u63d0\u51fa\u3057\u305f\u7d71\u8a08\u30d9\u30fc\u30b9\u306e\u4e88\u6e2c\u30e2\u30c7\u30eb\u3067\u3059\u3002\u3053\u306e\u30e2\u30c7\u30eb\u306f\u8ad6\u6587\u672c\u6587\u4e2d\u306b\u767b\u5834\u3057\u3001\u6700\u826f\u306e3\u30e2\u30c7\u30eb\u306e1\u3064\u3068\u8a55\u4fa1\u3055\u308c\u3066\u3044\u307e\u3059\u3002
\n \u3053\u306e\u30e2\u30c7\u30eb\u306e\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u30bb\u30c3\u30c8\u306b\u306f\u3001\u4e3b\u50ac\u8005\u304c\u914d\u5e03\u3057\u305f\u7b2c1\u56de\u30c1\u30e3\u30ec\u30f3\u30b8\u306b\u304a\u3051\u308bPhase1,2,3\u306e\u30c7\u30fc\u30bf\u306b\u52a0\u3048\u3066\u3001\u65e2\u77e5\u306eAmes\u8a66\u9a13\u306e\u7d50\u679c\u3092\u307e\u3068\u3081\u305f\u300cHansen\u306e\u30c7\u30fc\u30bf\u300d\u3068\u3044\u3046\u6709\u540d\u306a\u30c7\u30fc\u30bf\u30bb\u30c3\u30c8\u3092\u4f7f\u7528\u3057\u3066\u3044\u307e\u3059\u3002
\n \u8a18\u8ff0\u5b50\u306e\u7b97\u5b9a\u306b\u4f7f\u7528\u3057\u305f\u30a2\u30d7\u30ea\u30b1\u30fc\u30b7\u30e7\u30f3\u306f\u3001Dragon\u3068MOE<\/span><\/strong>\u3067\u3059\u3002
\n \u307e\u305f\u3001\u6a5f\u68b0\u5b66\u7fd2\u5668\u306b\u306fLight GBM\u3001Deep Learning\u3001Graph Convolutional Network<\/span><\/strong>\u3092\u4f7f\u7528\u3057\u3066\u3044\u307e\u3059\u3002
\n \u3053\u308c\u3089\u306e\u6a5f\u68b0\u5b66\u7fd2\u5668\u3092\u30b9\u30bf\u30c3\u30ad\u30f3\u30b0\u3059\u308b\u3053\u3068\u306b\u3088\u3063\u3066\u6700\u7d42\u7d50\u679c\u3092\u51fa\u529b\u3057\u307e\u3057\u305f\u3002<\/p>\n

 <\/p>\n

\n 4\u4f4d\u306eMMI-VOTE2\uff08\u660e\u6cbb\u85ac\u79d1\u5927\u5b66\uff09<\/span><\/strong>\u3082\u7b2c2\u56de\u30c1\u30e3\u30ec\u30f3\u30b8\u3067\u79c1\u305f\u3061\u304c\u63d0\u51fa\u3057\u305f\u7d71\u8a08\u30d9\u30fc\u30b9\u306e\u4e88\u6e2c\u30e2\u30c7\u30eb\u3067\u3059\u3002
\n \u3053\u306e\u30e2\u30c7\u30eb\u306e\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u30bb\u30c3\u30c8\u3082MMI-STK2\u3068\u540c\u69d8\u306b\u4e3b\u50ac\u8005\u304c\u914d\u5e03\u3057\u305f\u7b2c1\u56de\u30c1\u30e3\u30ec\u30f3\u30b8\u306b\u304a\u3051\u308bPhase1,2,3\u306e\u30c7\u30fc\u30bf\u306b\u52a0\u3048\u3066\u3001Hansen\u306e\u30c7\u30fc\u30bf\u30bb\u30c3\u30c8\u3092\u4f7f\u7528\u3057\u3066\u3044\u307e\u3059\u3002
\n \u3053\u306e\u30e2\u30c7\u30eb\u306b\u306f\u3001Dragon\u3068MOE<\/span><\/strong>\u304b\u3089\u8a08\u7b97\u3055\u308c\u305f\u8a18\u8ff0\u5b50\u3068\u3068\u3082\u306b\u3001DNA\u65ad\u7247\u3068\u306e\u30c9\u30c3\u30ad\u30f3\u30b0\u30b7\u30df\u30e5\u30ec\u30fc\u30b7\u30e7\u30f3\u306b\u3088\u308b\u89aa\u548c\u6027\u30b9\u30b3\u30a2<\/span><\/strong>\u3092\u8aac\u660e\u5909\u6570\u306b\u52a0\u3048\u3066\u3044\u307e\u3059\u3002
\n \u6a5f\u68b0\u5b66\u7fd2\u5668\u306b\u306fLight GBM\u3001Deep Learnig\u3001Random Forest\u3001Graph Convolutional Network<\/span><\/strong>\u3092\u4f7f\u7528\u3057\u3001\u6700\u7d42\u7d50\u679c\u3092\u591a\u6570\u6c7a<\/span><\/strong>\u306b\u3088\u3063\u3066\u6c7a\u5b9a\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n

 <\/p>\n

5\u4f4d\u306fMultiCASE\u793e\u306eBM PHARMA v1.5.2.0 (Statistical approach; SALM\/ECOLI consensus)<\/span><\/strong>\u3067\u3059\u3002\u3053\u306e\u30e2\u30c7\u30eb\u306f\u7b2c1\u56de\u30c1\u30e3\u30ec\u30f3\u30b8\u306e\u30d5\u30a7\u30fc\u30ba2\u3067\u63d0\u51fa\u3055\u308c\u3066\u3044\u307e\u3059\u3002
\n \u3053\u306e\u30e2\u30c7\u30eb\u306f\u30ab\u30d0\u30fc\u738765.3%\u3068\u3057\u3066\u63d0\u51fa\u3055\u308c\u3001\u305d\u306e\u6761\u4ef6\u306b\u304a\u3044\u3066\u30d0\u30e9\u30f3\u30b9\u7cbe\u5ea6\u3001MCC\u3001F1\u30b9\u30b3\u30a2\u3001PC1\u306b\u304a\u3044\u3066\u5168\u3066\u6700\u9ad8\u5f97\u70b9\u3092\u305f\u305f\u304d\u51fa\u3057\u3066\u3044\u307e\u3059\u3002\u3055\u3059\u304c\u306fMultiCASE\u793e\u3067\u3059\u304c\u3001\u30ab\u30d0\u30fc\u7387\u3092\u8abf\u6574\u3059\u308b\u3068\u7b2c5\u4f4d\u3068\u3044\u3046\u3053\u3068\u306b\u306a\u308a\u307e\u3057\u305f\u3002<\/p>\n

BM PHARMA\u306fCASE Ultra statistical-based<\/span><\/strong>\u3068\u3044\u3046QSAR\u306b\u57fa\u3065\u304f\u6bd2\u6027\u4e88\u6e2c\u30bd\u30d5\u30c8\u30a6\u30a7\u30a2\u304b\u3089\u8abf\u6574\u3055\u308c\u305f\u30b3\u30f3\u30da\u7528\u7279\u5225\u4ed5\u69d8\u306e\u30e2\u30c7\u30eb\u306e\u3088\u3046\u3067\u3059\u3002<\/p>\n

CASE Ultra\u306f\u3001\u69cb\u9020\u30a2\u30e9\u30fc\u30c8<\/span><\/strong>\u306e\u6709\u7121\u306b\u57fa\u3065\u3044\u3066\u6bd2\u6027\u3092\u4e88\u6e2c\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u30a2\u30e9\u30fc\u30c8\u306f\u6a5f\u68b0\u5b66\u7fd2\u3067\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u30c7\u30fc\u30bf\u304b\u3089\u81ea\u52d5\u7684\u306b\u62bd\u51fa\u3055\u308c\u307e\u3059\u3002\u88ab\u9a13\u5316\u5b66\u7269\u8cea\u306e\u6bd2\u6027\u4e88\u6e2c\u306f\u3001\u7279\u5b9a\u3055\u308c\u305f\u30a2\u30e9\u30fc\u30c8\u3068\u30a2\u30e9\u30fc\u30c8\u5468\u8fba\u306e\u69cb\u9020\u7684\u74b0\u5883\u306b\u4f9d\u5b58\u3057\u307e\u3059\u3002<\/p>\n

CASE Ultra\u306e\u4e3b\u306aAmes\u5909\u7570\u539f\u6027\u30e2\u30c7\u30eb\u306f\u3001GT1_AT_ECOLI\u3001GT1_A7B\u3001PHARM_ECOLI\u3001PHARM_SALM\u306e4\u3064\u306e\u30e2\u30b8\u30e5\u30fc\u30eb\u3067\u69cb\u6210\u3055\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u30b3\u30f3\u30da\u3067\u306f\u7279\u5225\u306b\u8a2d\u8a08\u3055\u308c\u305fSalmonella\/E Coli\u30b3\u30f3\u30bb\u30f3\u30b5\u30b9\u30e2\u30c7\u30eb<\/span><\/strong>\u3092\u4f7f\u7528\u3057\u305f\u3068\u306e\u3053\u3068\u3067\u3059\u3002<\/p>\n

\u69cb\u9020\u30a2\u30e9\u30fc\u30c8\u3092\u4f7f\u7528\u3057\u3066\u3044\u308b\u3053\u3068\u304b\u3089\u5316\u5b66\u69cb\u9020\u306b\u5bfe\u3059\u308b\u8aac\u660e\u6027\u304c\u9ad8\u3044\u30b7\u30b9\u30c6\u30e0\u306b\u306a\u3063\u3066\u3044\u305d\u3046\u3067\u3059\u3002<\/p>\n

 <\/p>\n

6\u4f4d\u306fLharsa\u793e\u306eDerec Nexus v.4.2.0<\/span><\/strong>\u3067\u3059\u3002\u3053\u306e\u30e2\u30c7\u30eb\u3082\u7b2c1\u56de\u30c1\u30e3\u30ec\u30f3\u30b8\u306e\u30d5\u30a7\u30fc\u30ba2\u3067\u63d0\u51fa\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u3053\u306e\u30e2\u30c7\u30eb\u306f\u30ab\u30d0\u30fc\u7387100%\u3068\u3057\u3066\u63d0\u51fa\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u3061\u306a\u307f\u306b\u7b2c7\u4f4d\u3082Lharsa\u793e\u306eDerec Nexus v.6.0.1\uff08\u7b2c2\u56de\u30c1\u30e3\u30ec\u30f3\u30b8\uff09\u3067\u3057\u305f\u3002<\/p>\n

Lharsa\u793e\u306e\u5b89\u5b9a\u3057\u305f\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u3092\u3046\u304b\u304c\u3044\u77e5\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002
\n Derek\u306f\u3001\u77e5\u8b58\u30d9\u30fc\u30b9\u306e\u30a8\u30ad\u30b9\u30d1\u30fc\u30c8\u30eb\u30fc\u30eb\u30d9\u30fc\u30b9\u30b7\u30b9\u30c6\u30e0<\/span><\/strong>\u3067\u3059\u3002Derek\u306b\u542b\u307e\u308c\u308b\u77e5\u8b58\u30d9\u30fc\u30b9\u306f\u3001\u69cb\u9020\u30a2\u30e9\u30fc\u30c8\u3001\u4f8b\u793a\u5316\u5408\u7269\u3001\u4ee3\u8b1d\u6d3b\u6027\u5316\u3084\u30e1\u30ab\u30cb\u30ba\u30e0<\/span><\/strong>\u306b\u95a2\u3059\u308b\u77e5\u8b58\u3092\u6697\u9ed9\u7684\u306b\u8003\u616e\u3057\u305f\u30eb\u30fc\u30eb\u3067\u69cb\u6210\u3055\u308c\u3001\u4e88\u6e2c\u306b\u4f7f\u7528\u3057\u3066\u3044\u308b\u3068\u306e\u3053\u3068\u3067\u3059\u3002<\/p>\n

\u30eb\u30fc\u30eb\u30d9\u30fc\u30b9\u306e\u30b7\u30b9\u30c6\u30e0\u3067\u3042\u308b\u305f\u3081\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u30bb\u30c3\u30c8\u3084\u9069\u7528\u9818\u57df\u306f\u5229\u7528\u3067\u304d\u306a\u3044\u306e\u3067\u3059\u304c\u3001\u69cb\u9020\u5206\u985e\u6a5f\u80fd\u306b\u3088\u3063\u3066\u63a8\u8ad6\u30ec\u30d9\u30eb\u304cequivocal\u4ee5\u4e0a\u306e\u5316\u5408\u7269\u306e\u5834\u5408\u306f\u30dd\u30b8\u30c6\u30a3\u30d6\u4e88\u6e2c\u3068\u3057\u3066\u6271\u308f\u308c\u307e\u3057\u305f\u3002<\/p>\n

\u77e5\u8b58\u30d9\u30fc\u30b9\u3067\u69cb\u9020\u30a2\u30e9\u30fc\u30c8\u3092\u4f7f\u7528\u3057\u3066\u3044\u308b\u306e\u3067\u3001\u8aac\u660e\u6027\u304c\u9ad8\u3044\u30b7\u30b9\u30c6\u30e0\u306b\u306a\u3063\u3066\u3044\u308b\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002<\/p>\n

 <\/p>\n

\u4ee5\u4e0a\u306e\u6240\u611f\u3068\u3057\u3066\u3001<\/span>\u5b9f\u969b\u306e\u6bd2\u6027\u8a55\u4fa1\u306e\u73fe\u5834\u3067\u4f7f\u7528\u3055\u308c\u3066\u3044\u308bCASE Ultra\u3084Derec Nexus\u306f\u8aac\u660e\u6027\u3092\u7dad\u6301\u3059\u308b\u3068\u3044\u3046\u5236\u7d04\u306e\u4e2d\u3067\u9ad8\u5ea6\u306a\u4e88\u6e2c\u3092\u9054\u6210\u3057\u3066\u3044\u308b\u306e\u304c\u7d20\u6674\u3089\u3057\u3044\u3068\u3053\u308d\u3060\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002<\/span><\/p>\n

\u4e00\u65b9\u3001\u79c1\u305f\u3061\u306e\u4e88\u6e2c\u30e2\u30c7\u30eb\u306f\u8aac\u660e\u6027\u3092\u5ea6\u5916\u8996\u3057\u3066\u9ad8\u3044\u8b58\u5225\u6027\u80fd\u3092\u76ee\u6307\u3057\u305f\u30e2\u30c7\u30eb\u3060\u3063\u305f\u3068\u8a00\u3048\u307e\u3059\u3002<\/span><\/p>\n

\u307e\u3042\u3001\u30b3\u30f3\u30da\u3067\u3057\u305f\u306e\u3067\u305d\u3046\u306a\u308b\u306e\u304c\u5f53\u7136\u306a\u306e\u3067\u3059\u304c\u30fb\u30fb\u30fb\u3002<\/span><\/p>\n

 <\/p>\n

\u6b21\u306b\u3001\u771f\u306e\u4e88\u6e2c\u6027\u80fd\u304c\uff11\u4f4d\u306e\u660e\u6cbb\u85ac\u79d1\u5927\u5b66\u306eMMI-STK1\u304c\u30ab\u30d0\u30fc\u7387\u3092\u8a2d\u5b9a\u3059\u308b\u3068\u3001\u3069\u3053\u307e\u3067\u6027\u80fd\u304c\u4e0a\u304c\u3063\u3066\u3044\u304f\u306e\u304b\u3092\u63a8\u5b9a\u3057\u3066\u307f\u305f\u3044\u3068\u601d\u3044\u307e\u3059\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

\u7b2c1\u56de\u304a\u3088\u3073\u7b2c2\u56deAmes\/QSAR\u56fd\u969b\u30c1\u30e3\u30ec\u30f3\u30b8\u30d7\u30ed\u30b8\u30a7\u30af\u30c8\u306b\u63d0\u51fa\u3055\u308c\u305f\u5168109\u30e2\u30c7\u30eb\u3092\u7cbe\u67fb\u3057\u305f\u7d50\u679c\u3001\u5168\u30c6\u30b9\u30c8\u5316\u5408\u7269\u3092\u4e88\u6e2c\u3057\u305f\uff08\u30ab\u30d0\u30fc\u7387100%\uff09\u3068\u4eee\u5b9a\u3057\u305f\u3068\u304d\u306e\u6700\u826f\u306e\u4e88\u6e2c\u30e2\u30c7\u30eb\u306f\u3001\u660e\u6cbb\u85ac\u79d1\u5927\u5b66\u306eMMI-STK1\u3067\u3042\u308b […]<\/p>\n","protected":false},"author":11,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"vkexunit_cta_each_option":"","footnotes":""},"categories":[18],"tags":[20,21],"class_list":["post-2948","post","type-post","status-publish","format-standard","hentry","category-blog","tag-ames","tag-qsar"],"_links":{"self":[{"href":"https:\/\/u-lab2.my-pharm.ac.jp\/~mminfo\/wp-json\/wp\/v2\/posts\/2948","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/u-lab2.my-pharm.ac.jp\/~mminfo\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/u-lab2.my-pharm.ac.jp\/~mminfo\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/u-lab2.my-pharm.ac.jp\/~mminfo\/wp-json\/wp\/v2\/users\/11"}],"replies":[{"embeddable":true,"href":"https:\/\/u-lab2.my-pharm.ac.jp\/~mminfo\/wp-json\/wp\/v2\/comments?post=2948"}],"version-history":[{"count":0,"href":"https:\/\/u-lab2.my-pharm.ac.jp\/~mminfo\/wp-json\/wp\/v2\/posts\/2948\/revisions"}],"wp:attachment":[{"href":"https:\/\/u-lab2.my-pharm.ac.jp\/~mminfo\/wp-json\/wp\/v2\/media?parent=2948"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/u-lab2.my-pharm.ac.jp\/~mminfo\/wp-json\/wp\/v2\/categories?post=2948"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/u-lab2.my-pharm.ac.jp\/~mminfo\/wp-json\/wp\/v2\/tags?post=2948"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}